产品编号：M327035

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	M327035
名称:	Methylbenzyl Nimesulide
别名:	2-(4-(Benzyloxy)phenoxy)-1-((methylsulfonyl)methyl)-4-nitrobenzene
分子式:	C₂₀H₁₈N₂O₆S
分子量:	414.43
种类:	Building Blocks; Miscellaneous;
应用:	Methylbenzyl Nimesulide is an intermediate in the synthesis of 4’-Hydroxy Nimesulide (H948560), the main metabolite of Nimesulide (N477500), an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.
参考文献	Pairet, M., et al.: Inflamm. Res., 47, S93 (1998); Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998); Okajima., E., et al.: Cancer Res., 58, 3028 (1998); Azab, A., et al.: Life Sci., 63, 323 (1998)