产品编号：M326296

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	M326296
名称:	Nilotinib 3-Imidazolyl N-oxide
别名:	Nilotinib Impurity; 4-Methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl]amino-N-(5-(3-oxo-4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamine
CAS号:	2139382-75-3
分子式:	C₂₈H₂₂F₃N₇O₂
外观:	淡黄色固体
熔点:	>156°C (dec.)
分子量:	545.52
储存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol (Slightly, Heated)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-Methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl]amino-N-(5-(3-oxo-4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamine is an impurity compound of Nilotinib (N465300), useful in the treatment of chronic myelogenous leukemia.
参考文献	Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),