产品编号：M325468

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	M325468
名称:	N-Methyl Pemetrexed Dimethyl Ester
别名:	N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl] L-Glutamic Acid 1,5-Dimethyl Ester
分子式:	C₂₃H₂₇N₅O₆
外观:	Brown Solid
分子量:	469.49
溶解度:	Dichloromethane, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Methyl Pemetrexed Dimethyl Ester is an intermediate in the synthesis of N-Methyl Pemetrexed (Pemetrexed EP Impurity A) which is an impurity of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.
参考文献	Kjell, D.P., et al.: Org. Proc. Res. Develop., 9, 738 (2005);