产品编号：M322025

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	M322025
名称:	(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
别名:	(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester
CAS号:	1168150-46-6
分子式:	C₁₈H₁₅NO₄
外观:	淡黄色固体
熔点:	>220ºC (dec.)
分子量:	309.32
储存:	冰箱, under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity.
参考文献	Xu, R., et al.: J. Labelled Comp. Radiopharm., 58, 308 (2015);