产品编号：M298220

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	M298220
名称:	Methyl 2-deoxy-D-erythro-pentopyranoside(Decitabine Impurity(Mixture of α/β isomers)
CAS号:	863396-35-4
参考CAS号:	α-Isomer: 6160-56-1/ β-Isomer: 17676-20-9
分子式:	C₆H₁₂O₄
分子量:	148.16
种类:	Standards; Carbohydrates and Oligosaccharides;
应用:	Methyl 2-deoxy-D-erythro-pentopyranoside is an impurity of Decitabine (α-isomer: D226730), a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, “normalizing” gene expression in cancerous cells.
参考文献	Aribi, A., et al.: Cancer, 109, 713 (2007); Issa, J., et al.: Blood, 103, 1635 (2004); Kantarjian , H., et al.: Cancer, 98, 522 (2003); Momparler, R., et al.: Anti-Cancer Drug., 8, 358 (1997); Plimack, E., et al.: Leukemia Lymphoma, 48, 1472 (2007)