产品编号：M295355

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	M295355
名称:	Methyl 2-Bromo-4-(4-octylphenyl)butanoate
分子式:	C₁₉H₂₉BrO₂
外观:	Light Yellow Oil
分子量:	369.34
溶解度:	DCM, Ethyl Acetate, Hexane
种类:	Building Blocks; Miscellaneous;
应用:	Methyl 2-Bromo-4-(4-octylphenyl)butanoate is an intermediate in the synthesis of N-[2(4-(-Octylphenyl))butanoic Acid] Fingolimod,which is an impurity of Fingolimod (F805000, HCl salt). Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.
参考文献	Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),