产品编号：M265615

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	M265615
名称:	N-[3-Methyl-2-phenylbutyl]-2-[4-isobutylphenyl]propionamide (PBA Amide)
分子式:	C₂₄H₃₃NO
分子量:	351.52
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-[3-Methyl-2-phenylbutyl]-2-[4-isobutylphenyl]propionamide (PBA Amide) is the impurity of rac Ibuprofen (I140000), which is a selective cyclooxygenase inhibitor (IC50=14.9uM). Also, it inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen has been shown to reduce Ebola infection in rodents. This compound is a contaminant of emerging concern (CECs).
参考文献	Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016);