产品编号：M265600

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	M265600
名称:	2-[1-Methoxy-2-(1-naphthalenyl)ethylidene]propanedinitrile
别名:	[1-Methoxy-2-(1-naphthalenyl)ethylidene]propanedinitrile;
CAS号:	221243-13-6
分子式:	C₁₆H₁₂N₂O
分子量:	248.28
种类:	Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-[1-Methoxy-2-(1-naphthalenyl)ethylidene]propanedinitrile is an intermediate used in the synthesis of 4-Amino-1-tert-butyl-3-(1’-naphthylmethyl)pyrazolo[3,4-d]pyrimidine (A603003), which is a highly potent (IC50=4.3 nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase.
参考文献	Bishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999), Davies, S., et al.: Biochem. J., 351, 95 (2000), Regan, J., et al.: J. Med. Chem., 45, 2994 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Kuma, Y., et al.: J. Biol. Chem., 280, 19472 (2005)