产品编号：M265075

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	M265075
名称:	(3-Methylaminopropyl)-5H-dibenz[b,f]azepine
别名:	N-Methyl-5H-dibenz[b,f]azepine-5-propanamine; 5-[3-(Methylamino)propyl]-5H-Dibenz[b,f]azepine; G 35967;
CAS号:	2010-13-1
分子式:	C₁₈H₂₀N₂
分子量:	264.36
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(3-Methylaminopropyl)-5H-dibenz[b,f]azepine, is an impurity of Desipramine (D290050), a tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter. It is also related to the antidepressive drug Imipramine (I465980), having capacity to inhibit the uptake of 5-hydoxy tryptamine (5-HT) by human platelets in vitro.
参考文献	Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),; Todrick, A., et al.: J. Pharm. Pharmacol., 21, 751 (1969);