产品编号：M252850

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	M252850
名称:	N-(2-Mercaptoethyl) Demecolcine
别名:	(7S)-6,7-Dihydro-7-[(2-mercaptoethyl)methylamino]-1,2,3,10-tetramethoxy-benzo[a]heptalen-9(5H)-one;
CAS号:	1217746-74-1
分子式:	C₂₃H₂₉NO₅S
外观:	Yellow Solid
分子量:	431.55
溶解度:	Chloroform, Dichlormethane, DMSO, Ethanol, Ethyl Acetate, Methanol
种类:	Standards; Enzyme Activators and Inhibitors;
应用:	An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
参考文献	Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),