产品编号：M219023

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	M219023
名称:	(2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylate
别名:	(2R,5S)-5-(4-Amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester
参考CAS号:	Unlabelled: 147027-10-9
分子式:	C₁₇¹³CH₂₇N₃O₄S
分子量:	382.48
种类:	Building Blocks; Isotopic Labeled Analogues;
应用:	(2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylate is a labeled analogue of (2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylate (M219020), an intermediate in the synthesis of Lamivudine (L172500), a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.
参考文献	Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992); Jeong, L., et al.: J. Med. Chem., 36, 181 (1993); Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977)