产品编号：M162005

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	M162005
名称:	Manassantin A
别名:	(αR,α'R)-α,α'-[[(2S,3R,4R,5S)-Tetrahydro-3,4-dimethyl-2,5-furandiyl]bis[(2-methoxy-4,1-phenylene)oxy-(1R)-ethylidene]]bis[3,4-dimethoxy-benzenemethanol; (-)-Manassantin A; HNP 98701C; Saucernetin A;
CAS号:	88497-87-4
分子式:	C₄₂H₅₂O₁₁
分子量:	732.86
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Manassantin A is a potent inhibitor of hypoxia-inducible factor 1 (HIF-1) activity. Also, it is an herbal medicine isolated from Saururus chinensis which inhibits 5-lipoxygenase (5-LO)-dependent leukotriene C4 (LTC4) generation in bone marrow-derived mast cells (BMMCs)
参考文献	Kwon, D., et al.: J. Med. Chem., 58, 7659-7671 (2015); Lang, L., et al.: PLoS One, 9, e99584/1-e99584/9 (2014); Kim, S. J., et al.: Biol. Pharm. Bull., 34, 1769-1772 (2011)