产品编号：M154170

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	M154170
名称:	Carfilzomib 2-Acetate
别名:	(4S,7S,10S,13R,15R)-10-Benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14-pentaoxo-4-phenethyl-3,6,9,12-tetraazahexadecan-16-yl Acetate; (αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1R,3R)-4-(acetyloxy)-3-hydroxy-3-methyl-1-(2-methylpropyl)-2-oxobutyl]-L-phenylalaninamide
分子式:	C₄₂H₆₁N₅O₉
外观:	Solid
分子量:	779.96
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Carfilzomib 2-Acetate is an intermediate in the synthesis of Carfilzomib (2R,4R)-Diol (C183525), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
参考文献	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);