Lomeguatrib

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产品编号:L469700

产品规格:250mg

产品价格:面议


产品详情

标准品编号: L469700
名称: Lomeguatrib
别名: 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine; 6-[(4-Bromo-2-thienyl)methoxy] -1H-purin-2-amine; 2-Amino-6-(4-bromothiophen-2-ylmethoxy)-9H-purine; PaTrin 2;
CAS号: 192441-08-0
分子式: C₁₀H₈BrN₅OS
分子量: 326.17
种类: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Lomeguatrib is an inhibitor of O6-methylguanine-DNA methyltransferase (MGMT). Lomeguatrib attenuates MGMT activity in vitro and in vivo. Lomeguatrib enhances the antitumor activity of temozolomide in both human melanoma and MCF-7 xenografts.
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