产品编号：L469290

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	L469290
名称:	LM 22A4
别名:	N1,N3,N5-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide; N,N’,N’’-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide; N,N’,N’’-Tris(β-hydroxyethyl)trimesamide;
CAS号:	37988-18-4
分子式:	C₁₅H₂₁N₃O₆
分子量:	339.34
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	LM 22A4 is a potent tropomyosin-related kinase B (TrkB) agonist. LM 22A4 has been show to induce activation of Trk, Akt and ERK in mouse hippocampus and striatum and reverse deficits in motor task learning in mice following traumatic brain injury. LM 22A4 also restored respiratory function in a rat model of Rett syndrome.
参考文献	Massa, S.M. et al.: J. Clin. Invest., 120, 1774 (2010); Schmid, D.A. et al.: J. Neurosci., 32, 1803 (2012);