产品编号：L215175

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	L215175
名称:	Lithium (S)-1-(tert-Butoxy)-2-cyano-4-(2-fluoro-[1,1'-biphenyl]-4-yl)-1,3-dioxopentan-2-ide
CAS号:	215176-01-5
分子式:	C₂₂H₂₁FLiNO₃
分子量:	373.35
种类:	Building Blocks; Chiral Molecules;
应用:	Lithium (S)-1-(tert-Butoxy)-2-cyano-4-(2-fluoro-[1,1'-biphenyl]-4-yl)-1,3-dioxopentan-2-ide is an intermediate in the synthesis of Rimacalib (R505015), an inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib.
参考文献	Westra, Johanna., et al.: BMC Musculoskelet Disord.,11 ,No pp. given.(2010);