产品编号：L178790
产品规格：5mg
产品价格：面议
| 标准品编号: | L178790 |
| 名称: | LB 42708 |
| 别名: | 4-[[1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]carbonyl]morpholine; [1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]-4-morpholinylmethanone; (1-((1-(4-Bromobenzyl)-1H-imidazol-5-yl)methyl)-4-(naphthalen-1-yl)-1H-pyrrol-3-yl)(morpholino)methanone |
| CAS号: | 226929-39-1 |
| 分子式: | C₃₀H₂₇BrN₄O₂ |
| 外观: | 白色固体 |
| 熔点: | 165-169ºC |
| 分子量: | 555.46 |
| 储存: | -20°C Freezer |
| 溶解度: | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| 种类: | Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | LB 42708 is a selective nonpeptidic Farnesyltransferase (FTase) inhibitor.LB42708 suppresses tumor growth and tumor angiogenesis in both xenograft tumor models of Ras-mutated HCT116 cells and its wild-type Caco-2 cells, indicating its potential application in the treatment of both Ras-mutated and wild type tumors. |
| 参考文献 | |
