产品编号:L176100
产品规格:25mg
产品价格:面议
| 标准品编号: | L176100 |
| 名称: | LAS 101057 |
| 别名: | N-[5-(3-Fluoro-4-pyridinyl)-6-(3-pyridinyl)-2-pyrazinyl]cyclopropanecarboxamide |
| CAS号: | 925676-48-8 |
| 分子式: | C₁₈H₁₄FN₅O |
| 分子量: | 335.34 |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | LAS 101057 is a potent, selective, and orally efficacious A2B receptor antagonist, was identified as a clinical development candidate. It inhibits agonist-induced IL-6 production in human fibroblasts and is active in an ovalbumin (OVA)-sensitized mouse model after oral administration, reducing airway hyperresponsiveness to methacholine, Th2 cytokine production and OVVIP(LA)specific IgE levels. |
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