LAS 101057

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产品编号:L176100

产品规格:25mg

产品价格:面议


产品详情

标准品编号: L176100
名称: LAS 101057
别名: N-[5-(3-Fluoro-4-pyridinyl)-6-(3-pyridinyl)-2-pyrazinyl]cyclopropanecarboxamide
CAS号: 925676-48-8
分子式: C₁₈H₁₄FN₅O
分子量: 335.34
种类: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: LAS 101057 is a potent, selective, and orally efficacious A2B receptor antagonist, was identified as a clinical development candidate. It inhibits agonist-induced IL-6 production in human fibroblasts and is active in an ovalbumin (OVA)-sensitized mouse model after oral administration, reducing airway hyperresponsiveness to methacholine, Th2 cytokine production and OVVIP(LA)specific IgE levels.
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