产品编号：KIT7770
产品规格：
产品价格：面议
| 标准品编号: | KIT7770 |
| 名称: | Abacavir (1.0 mg/mL in Methanol) |
| 别名: | (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1S-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; 1592U89; ABC; Abacavir API; |
| CAS号: | 136470-78-5 |
| 分子式: | C₁₄H₁₈N₆O |
| 外观: | Colourless Solution |
| 熔点: | N/A |
| 分子量: | 286.33 |
| 储存: | -20°C Freezer |
| 溶解度: | Methanol |
| 种类: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Solutions; Kits; |
| 应用: | Abacavir (Abacavir API) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. |
| 危险品: | Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |
| 参考文献 | |
