4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (1.0 mg/mL in Methanol)

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产品编号:KIT0575

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产品价格:面议


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标准品编号: KIT0575
名称: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (1.0 mg/mL in Methanol)
别名: 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; NNK;
CAS号: 64091-91-4
分子式: C₁₀H₁₃N₃O₂
外观: Colourless Solution
熔点: N/A
分子量: 207.23
储存: Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度: Methanol
稳定性: Light Sensitive
种类: Standards; Stimulant; Nicotine Derivatives and Metabolites; Solutions; Kits;
应用: General Uses: Nicotine Testing, Environmental Monitoring and testing of nicotine biomarkers. Description: The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a powerful lung carcinogen in animal models at a dose of 25mg/kg body weight (1) . NNK is considered “carcinogenic to humans” by the International Agency for Research on Cancer (2). NNK induce carcinogenesis by causing DNA adductions and mutations as well as promoting tumor growth through receptor-mediated effects (3). Nicotine can undergo chemical conversions into carcinogenic NNK during the process of curing & smoking (4) .
危险品: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
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