产品编号：K660455

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	K660455
名称:	KW 3902
别名:	8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione; 8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione (9CI); 2,5-Methanopentalene, 1H-Purine-2,6-dione Derivative; Rolofylline
CAS号:	136199-02-5
分子式:	C₂₀H₂₈N₄O₂
分子量:	356.46
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	KW 3902 is an adenosine A1-receptor antagonist, which has recently been shown to alleviate axonopathy caused by human Tau ΔK280. KW 3902 can be considered for the development of a treatement towards hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases.
参考文献	Massie, B.M.; et al.: N. Engl. J. Med., 363, 1419 (2010); Dennissen, F.J.; et al: Proc. Natl. Acad. Sci. U.S.A., 113, 11597 (2016)