产品编号：K200710
产品规格：25mg
产品价格：面议
| 标准品编号: | K200710 |
| 名称: | 6’-Ketopravastatin Lactone |
| 别名: | (2S)-(1S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-7-methyl-3-oxo-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl (2S)-2-Methyl-butanoic Acid Ester; SQ 31553; [1S-[1α(R*),7β,8β(2S*,4S*),8aβ]]-1,2,3,7,8,8a-Hexahydro-7-methyl-3-oxo-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2-Methyl-butanoic Acid Ester; |
| CAS号: | 124773-83-7 |
| 分子式: | C₂₃H₃₂O₆ |
| 分子量: | 404.5 |
| 种类: | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | 6’-Ketopravastatin Lactone is a metabolite of Pravastatin Sodium via enzymically dehydrogenation, which exhibits β-hydroxydehydrogenase activity; Also, it is an intermediate used in the synthesis of Pravastatin 6-Ketone Sodium Salt (P702050), which is an impurity of Pravastatin Sodium (P702000), which is a competitive inhibitor of HMG-CoA reductase. It can be used as a drug to for lowering cholesterol and preventing cardiovascular disease. |
| 参考文献 | |
