产品编号：K170985

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	K170985
名称:	3-keto-5β-Abiraterone
别名:	(5β)-17-(3-Pyridinyl)androst-16-en-3-one
CAS号:	1940175-99-4
分子式:	C₂₄H₃₁NO
分子量:	349.51
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-keto-5β-Abiraterone is a metabolite of abiraterone (A108490) which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
参考文献	Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005);