产品编号：I872280

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	I872280
名称:	Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate
别名:	Isopropyl (4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate;
分子式:	C₁₇H₁₉N₃O₄
外观:	Light Pink to Orange Solid
熔点:	>62°C (dec.)
分子量:	329.35
储存:	冰箱
溶解度:	Chloroform (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate is an impurity in the synthesis of Sorafenib (S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
参考文献	Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),

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