产品编号：I824640
产品规格：10g
产品价格：面议
| 标准品编号: | I824640 |
| 名称: | Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt |
| 别名: | N-(Hydroxyphenoxyphosphinyl)-L-alanine 1-Methylethyl Ester Sodium Salt; (2S)-Isopropyl 2-((Hydroxy(phenoxy)phosphoryl)amino)propanoate Sodium Salt |
| 参考CAS号: | free acid: 1520010-86-9 |
| 分子式: | C₁₂H₁₇NNaO₅P |
| 分子量: | 309.23 |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt is an impurity of Sofosbuvir (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
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