产品编号：I823430

产品规格：2.5g

产品价格：面议

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产品详情

标准品编号:	I823430
名称:	(rac)-4-(3-Isopropoxyphenyl)-3,4-dimethylpiperidine Hydrochloride
别名:	(rac)-3,4-Dimethyl-4-[3-(1-methylethoxy)phenyl]-piperidine Hydrochloride
参考CAS号:	Free Base: 1246923-40-9
分子式:	C₁₆H₂₆ClNO
分子量:	283.84
种类:	Research Tools;
应用:	(rac)-4-(3-Isopropoxyphenyl)-3,4-dimethylpiperidine is an impurity in the preparation of (3R,4R)-3-(3,4-Dimethyl-4-piperidinyl)phenol, an intermediate in the synthesis of Alvimopan(A575800), a peripheral µ-opioid receptor antagonist.
参考文献	Reddy, B.R., et. al.: Org. Process Res. Dev., 18, 163 (2014); Zimmerman, D.M., et al.: J. Med. Chem., 37, 2262 (1994); Liu, S.S., et al.: Clin. Pharmacol. Ther., 68, 66 (2000); Taguchi, A., et al.: N. Engl. J. Med., 345, 935 (2001)