产品编号：I814125

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	I814125
名称:	Isodemecolcine
别名:	(S)-6,7-Dihydro-1,2,3,9-tetramethoxy-7-(methylamino)-benzo[a]heptalen-10(5H)-one; Isocolchicine;
CAS号:	4702-33-4
分子式:	C₂₁H₂₅NO₅
分子量:	371.43
种类:	Standards; Enzyme Activators and Inhibitors;
应用:	An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
参考文献	Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),