产品编号：I666675

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	I666675
名称:	Intedanib Piperazinyl N,N'-Dioxide
别名:	(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(1,4-dioxido-4-methylpiperazin-1-yl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester; Intedanib Impurity H;
分子式:	C₃₁H₃₃N₅O₆
分子量:	571.62
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Intedanib Piperazinyl N,N'-Dioxide is a derivative of Intedanib (I666650). Intedanib is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. Also, aAn antitumor agent.
参考文献	Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)