产品编号：I387525

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	I387525
名称:	3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline
CAS号:	943320-48-7
分子式:	C₁₀H₈F₃N₃
分子量:	227.19
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline is a reactant used in the synthesis of novel Bcr/Abl inhibitors as anti-cancer drugs. Nilotinib (N465300) impurity, which might be useful in treatment of chronic myelogenous leukemia.
参考文献	Wang, D. et al.: Bioorg. Med. Chem. Lett., 21, 1965 (2011); Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),