产品编号：I355005

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	I355005
名称:	N-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]Benzamide
别名:	Desmethylimidazole Nilotinib
CAS号:	2119583-26-3
分子式:	C₂₇H₂₀F₃N₇O
外观:	Pale Yellow to Pale Beige Solid
熔点:	>245°C (dec.)
分子量:	515.49
储存:	Referigerator
溶解度:	DMSO (Slightly), Methanol (Very Slightly, Heated)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]Benzamide, is an imurtiy of Nilotinib (N465300), that might be useful in treatment of chronic myelogenous leukemia.
参考文献	Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),