产品编号：I267302
产品规格：2.5mg
产品价格：面议
| 标准品编号: | I267302 |
| 名称: | Iloprost-d4 (Major) |
| 别名: | (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic Acid-d4; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane-d4; Ciloprost-d4; Endoprost-d4; Ilomedin-d4; ZK 36374-d4; |
| CAS号: | 1035094-10-0 |
| 参考CAS号: | 类似: 78919-13-8 |
| 分子式: | C₂₂H₂₈D₄O₄ |
| 外观: | Colorless to Pale Yellow Oil |
| 熔点: | N/A |
| 分子量: | 364.51 |
| 储存: | Amber Vial, -86°C Freezer, Under inert atmosphere |
| 溶解度: | Benzene (Slightly) |
| 种类: | Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | A labelled synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. |
| 参考文献 | |
