产品编号：H954477

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	H954477
名称:	N-Hydroxy Ticagrelor-d7
别名:	(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]hydroxyamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol-d7
参考CAS号:	Unlabelled: 1644461-92-6
分子式:	C₂₃H₂₁D₇F₂N₆O₅S
分子量:	545.61
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Hydroxy Ticagrelor-d7 is the isotope labelled analog of N-Hydroxy Ticagrelor (H954475); a degradation product of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).
参考文献	Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007); Hassane, S.Y., et al.: J. Pharmaceut. Biomed., 105, 74 (2015)