产品编号：H952012

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	H952012
名称:	9-(2-Hydroxypropyl)adenine-13C5
别名:	6-Amino-α-methyl-9H-purine-9-ethanol-13C5; (RS)-9-(2-Hydroxypropyl)adenine-13C5; 9-(2-Hydroxyprop-1-yl)adenine-13C5; DL-9-(2-Hydroxypropyl)adenine13C5; DL-6-amino-α-methyl-9H-Purine-9-ethanol-13C5; (±)-6-amino-α-methyl-9H-Purine-9-ethanol-13C5;
参考CAS号:	14047-26-8
分子式:	C₃¹³C₅H₁₁N₅O
分子量:	198.17
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	9-(2-Hydroxypropyl)adenine-13C5 is an intermediate used in the synthesis of rac Tenofovir-13C5 (>90%) (T018501), which is he isotope labelled analog of Tenofovir (T018500); an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Also used as an anti-HIV agent and antiviral.
参考文献	Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005); Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)