产品编号：H947928
产品规格：25mg
产品价格：面议
| 标准品编号: | H947928 |
| 名称: | 4-((1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzonitrile |
| 别名: | Crisaborole, 4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]benzonitrile, 5-(4-Cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole, 5-(4-Cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole, AN2728 |
| CAS号: | 906673-24-3 |
| 分子式: | C₁₄H₁₀BNO₃ |
| 外观: | 白色至淡黄色固体 |
| 熔点: | >130°C (softened) |
| 分子量: | 251.05 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 种类: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | A series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-(4-Cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent. |
| 参考文献 | |
