产品编号：H947760

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	H947760
名称:	(S)-4-Hydroxymethyl Ambrisentan
别名:	(αS)-α-[[4-(Hydroxymethyl)-6-methyl-2-pyrimidinyl]oxy]-β-methoxy-β-phenylbenzenepropanoic Acid
CAS号:	1106685-66-8
分子式:	C₂₂H₂₂N₂O₅
外观:	白色固体
熔点:	>130ºC (dec.)
分子量:	394.42
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S)-4-Hydroxymethyl Ambrisentan is a metabolite of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.
参考文献	Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996); Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002); Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003)