产品编号：H946945

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	H946945
名称:	5-(Hydroxymethyl)-3-(4-octylbenzyl)-5-(4-octylphenethyl)morpholin-2-one
分子式:	C₃₆H₅₅NO₃
外观:	白色固体
分子量:	549.83
溶解度:	DCM, Ethyl Acetate
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	5-(Hydroxymethyl)-3-(4-octylbenzyl)-5-(4-octylphenethyl)morpholin-2-one is an intermediate in the synthesis of N-[2(4-(-Octylphenyl))butanoic Acid] Fingolimod,which is an impurity of Fingolimod (F805000, HCl salt). Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.
参考文献	Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),