产品编号：H942121

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	H942121
名称:	4-Hydroxy Estrone 1-N7-Guanine-15N5
别名:	2-Amino-7-(3,4-dihydroxy-17-oxoestra-1,3,5(10)-trien-1-yl)-1,7-dihydro-6H-purin-6-one-15N5; 4-OH-E1-1-N7Gua-15N5;
参考CAS号:	178971-92-1
分子式:	C₂₃H₂₅¹⁵N₅O₄
分子量:	440.44
种类:	Standards; Isotopic Labeled Analogues;
应用:	4-Hydroxy Estrone 1-N7-Guanine-15N5 is an labeled analog of H942120, which is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.
参考文献	Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),