产品编号:H941725
产品规格:250mg
产品价格:面议
| 标准品编号: | H941725 |
| 名称: | 6-Hydroxy-L-DOPA |
| 别名: | 2,4,5-Trihydroxy-L-phenylalanine; 2,4,5-Trihydroxyphenylalanine; 2,5-Dihydroxy-L-tyrosine; 3-(3,4,6-Trihydroxyphenyl)-L-alanine; 6-Hydroxy-L-DOPA; Hydroxy-L-dopa; L-6-Hydroxydopa; TOPA; Levodopa EP Impurity A; Levodopa USP Related Compound A |
| 杂质: | Levodopa EP Impurity A; Levodopa USP Related Compound A |
| CAS号: | 27244-64-0 |
| 分子式: | C₉H₁₁NO₅ |
| 外观: | Grey to Brown Solid |
| 熔点: | >190°C (dec.) |
| 分子量: | 213.19 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | Water (Slightly) |
| 种类: | Standards; Amino Acids; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | 6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase. |
| 参考文献 | |