产品编号：H939875

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	H939875
名称:	(E)-7-Hydroxy-5-methoxy-4-methyl-6-(2-(2-methyl-5-oxotetrahydrofuran-2-yl)vinyl)isobenzofuran-1(3H)-one
别名:	Mycophenolic Acid Impurity;
分子式:	C₁₇H₁₈O₆
分子量:	318.32
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(E)-7-Hydroxy-5-methoxy-4-methyl-6-(2-(2-methyl-5-oxotetrahydrofuran-2-yl)vinyl)isobenzofuran-1(3H)-one, is the vinyl analogue of Mycophenolic Acid (M831500), which is an immunosuppressant drug used to prevent rejection in organ transplantation. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
参考文献	Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),