产品编号：H939020

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	H939020
名称:	2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxylic acid
CAS号:	1245157-42-9
分子式:	C₁₅H₂₀N₆O₃S
分子量:	364.42
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxylic acid is an intermediate in the preparation of Dasatinib (D193600), a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.
参考文献	Lombardo, L.J., et al: J. Med. Chem., 47, 6658 (2004); Shah, N. P., et al.: Science, 305, 399 (2004); O’Hare, T., et al.: Curr. Opin. Genet. Dev., 16, 92 (2006); Yan, R., et al.: Faming Zhuanli Shenqing(2010),CN101845045A20100929