(R)-Hydroxy Des(boric Acid) Bortezomib

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产品编号:H935900

产品规格:25mg

产品价格:面议


产品详情

标准品编号: H935900
名称: (R)-Hydroxy Des(boric Acid) Bortezomib
别名: N-[(1S)-2-[[(1R)-1-Hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; N-[(1S)-2-[[(1R)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide;
杂质: Bortezomib USP Impurity I
CAS号: 289472-78-2
分子式: C₁₉H₂₄N₄O₃
外观: 白色至白色固体
熔点: 113 - 115°C
分子量: 356.42
储存: 冰箱
溶解度: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
种类: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: (R)-Hydroxy Des(boric acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
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