产品编号:H935900
产品规格:25mg
产品价格:面议
| 标准品编号: | H935900 |
| 名称: | (R)-Hydroxy Des(boric Acid) Bortezomib |
| 别名: | N-[(1S)-2-[[(1R)-1-Hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; N-[(1S)-2-[[(1R)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide; |
| 杂质: | Bortezomib USP Impurity I |
| CAS号: | 289472-78-2 |
| 分子式: | C₁₉H₂₄N₄O₃ |
| 外观: | 白色至白色固体 |
| 熔点: | 113 - 115°C |
| 分子量: | 356.42 |
| 储存: | 冰箱 |
| 溶解度: | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | (R)-Hydroxy Des(boric acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. |
| 参考文献 | |