产品编号：H828990

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	H828990
名称:	4-Hydroxy Atorvastatin-d5 Calcium Salt
别名:	(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid-d5 Calcium Salt; p-Hydroxyatorvastatin-d5 Calcium Salt;
参考CAS号:	类似: 1276537-18-8
分子式:	C₃₃H₂₈D₅CaFN₂O₆
分子量:	617.73
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A deuterated metabolite of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
参考文献	Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),