产品编号：H828961

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	H828961
名称:	4-Hydroxy Atorvastatin Hemicalcium Salt
别名:	(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid Hemicalcium Salt; p-Hydroxyatorvastatin Hemicalcium Salt
CAS号:	1263176-34-6
参考CAS号:	free acid: 214217-88-6
分子式:	C₆₆H₆₈CaF₂N₄O₁₂
外观:	白色至Light Beige Solid
熔点:	>190°C (dec.)
分子量:	1187.34
储存:	Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
参考文献	Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);

Download MSDS File