产品编号：H828952

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	H828952
名称:	2-Hydroxy Atorvastatin-d5 Sodium Salt
别名:	(βR,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[(2-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-(phenyl-d5)-1H-pyrrole-1-heptanoic Acid Sodium Salt; BMS 243887-01 Sodium Salt; PD 152873; o-Hydroxyatorvastatin Sodium Salt;
参考CAS号:	类似: 214217-86-4 (free acid)Disodium Salt:
分子式:	C₃₃H₃₀D₅FN₂O₆ •xNa
外观:	白色至Pale Beige Solid
熔点:	132-134°C
分子量:	579.67
储存:	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
溶解度:	Methanol (Slightly)
种类:	Standards; Chiral Molecules; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A deuterated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
参考文献	Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),

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