产品编号：H828802

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	H828802
名称:	2-Hydroxy Atorvastatin tert-Butyl Ester-d5
别名:	(3R,5R)-tert-Butyl 7-(2-(4-Fluorophenyl)-4-((2-hydroxyphenyl)carbamoyl)-5-isopropyl-3-phenyl-d5-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
参考CAS号:	Unlabelled racemic: 1346599-89-0
分子式:	C₃₇H₃₈D₅FN₂O₆
分子量:	635.78
种类:	Building Blocks; Miscellaneous;
应用:	2-Hydroxy Atorvastatin tert-Butyl Ester-d5 is an intermediate in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
参考文献	Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)