产品编号：H825610

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	H825610
名称:	4-Hydroxy-3-(hydroxymethyl)benzaldehyde
别名:	3-(Hydroxymethyl)-4-hydroxybenzaldehyde; Salbutamol Impurity Q;
CAS号:	54030-32-9
分子式:	C₈H₈O₃
分子量:	152.15
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-Hydroxy-3-(hydroxymethyl)benzaldehyde is an impurity of Albuterol (A514501) which is a β2-adrenoceptor agonist, a bronchodilator and a tocolytic. 4-Hydroxy-3-(hydroxymethyl)benzaldehyde is also used in the preparation of Cinnamyl alcohol-like compounds which can be used for treatment of free radical generated related diseases inlcuding auto-immunodeficiency diseases. It is also used as a reagent in the synthesis of 5-Diacetoxymethyl-cycloSal-d4TMP which is a prototype of enzymatically activated cycloSal-pronucleotides that may possess antiviral activities against HIV.
参考文献	Zhao, Y., et al.: Cinnamyl alcohol-like compounds, their preparation method and application, China Patent 101092336 Dec 26, 2007; Gisch, N., et al.: Nucleos. Nucleot. Nucl., 26, 861 (2007); Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),