产品编号：H804510

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	H804510
名称:	21β-Hydroxyeplerenone 3-Bis Ethyl Ketal
别名:	(2’R,4aS,4bR,4’R,5aR,6aS,9aS,9bR,10R)-Methyl 2,2-Diethoxy-4’-hydroxy-4a,6a-dimethyl-5’-oxo-3,4,4a,4’,5a,5’,6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3’H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2’-furan]-10-caboylate;
分子式:	C₂₈H₄₀O₈
分子量:	504.61
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
应用:	21β-Hydroxyeplerenone 3-Bis Ethyl Ketal is an intermediate used in the synthesis of 21β-Hydroxyeplerenone (H804505), which is a derivative of the parent compound Eplerenone (E588775), which is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
参考文献	de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),