产品编号：H716440

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	H716440
名称:	(αS)-α-Hydrazinyl-3,4-dimethoxy-α-methyl-benzenepropanoic Acid
别名:	L-α-Hydrazino-3,4-dimethoxy-α-methylbenzenepropanoic Acid; L-α-Hydrazino-α-methyl-β-(3,4-dimethoxyphenyl) Propionic Acid; L-α-Methyl-α-hydrazino-β-(3,4-dimethoxyphenyl)propionic Acid; L-α-Hydrazino-3,4-dimethoxy-α-methyl-hydrocinnamic Acid;
CAS号:	28860-96-0
分子式:	C₁₂H₁₈N₂O₄
分子量:	254.28
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(αS)-α-Hydrazinyl-3,4-dimethoxy-α-methyl-benzenepropanoic Acid is an intermediate used in the synthesis of (S)-(-)-Carbidopa (C175985), which is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.
参考文献	Henry, G.M. et al.: Psychosom. Med., 38, 95 (1976); Leguire, L.E. et al.: Invest. Ophthalmol. Vis. Sci. 34, 3090 (1993); Deleu, D. et al.: Naun. Schmied. Arch. Pharmacol. 348: 576 (1993);