产品编号：H714400

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	H714400
名称:	2-Hydrazinopyrazine
别名:	2(1H)-Pyrazinone Hydrazone; 2-Hydrazinylpyrazine; Hydrazinopyrazine; Pyrazinylhydrazine
CAS号:	54608-52-5
分子式:	C₄H₆N₄
分子量:	110.12
种类:	Building Blocks; Miscellaneous;
应用:	2-Hydrazinopyrazine is used as a reagent in the synthesis of Sitagliptin (S491000, H3PO4) and its analogs. Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor that has recently been approved for the therapy of type II diabetes.
参考文献	Kim, D., et al.: Bioorg. Med. Chem. Lett., 17, 3373 (2007); Hansen, K.B., et al.: Org. Process Res. Dev., 9, 634 (2005); Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005); Bergman, A., et al: Clin. Ther. 28, 55 (2006)