产品编号：H448750

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	H448750
名称:	2-(Hydroxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
CAS号:	144875-91-2
分子式:	C₁₅H₁₇N₃O₂
外观:	Pale Solid
分子量:	271.31
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-(Hydroxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol is an intermediate in the synthesis of O-deethylated Resiquimod (D228575), which is derived from its parent compound Resiquimod (R144680), which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
参考文献	Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);